I have been looking for a simple piece of software such as this for some time now. I have a very good idea what files are taking up space but this software puts the drives and folders in perspective, you can keep drilling down into folders and subfolders, giving you nice pie charts or bar charts. One of the drawbacks is that you can’t open the folder directly from the software, you would have to go through explorer. Just a useful tool to give you perspective on your drives.
Link: LifeHacker (Freeware)